loading
NEWS
VR

Agitator Nutsche Filter Dryer - Sterilization Class

August 30, 2023

The steam sterilizing agitator nutsche filter dryer designed by Wuxi Zhanghua Pharmaceutical Equipment is for the sterile production process, from inert, feeding slurry, cleaning, drying, to the discharge of dry products.

CIP and SIP provide safe and convenient sterilization solutions, and automatic operation is easy to check. This equipment is suitable for filtration and drying in biotechnology and pharmaceutical fields under sterile environment.

The steam sterilization agitator nutsche filter dryer can meet the requirements of verifiable sterile operation during the filtration and drying process of APIs, intermediates and fine chemicals.

 

Working principle

 Inert

Before feeding the wet filter cake and filtrate, fill the container with nitrogen to remove the oxygen inside. This can prevent the potentially explosive atmosphere inside the container.

 

Feed

After inert, fill the filtrate in the container.

 

Filter

The filtrate is forced inside the container by nitrogen pressure, extending from the bottom of the filter cloth, the solids are retained on the cloth, and the mother liquid flows through the formed filter cake.

 

Clean

When the filtrate is separated from the filter cake, the cleaning process is started.

Before the replacement and washing, the surface of the filter cake is smoothed by agitator to prevent the filter cake from cracking.

The wash ring with nozzles evenly distributes the cleaning liquid over the surface of the entire filter cake. By re-pressurizing the container, the cleaning liquid flushes the filter cake, replaces the remaining mother liquid and drains the filtered mother liquid in the same way.

During the re-beating process, the cleaning liquid is added into the container and mixed with the material. By re-pressurizing the container, the cleaning liquid flushes the filter cake, replaces the remaining mother liquid and drains the filtered mother liquid in the same way.

 

Dry

After cleaning, the drying function is triggered. The vacuuming and heating of the dryer are carried out simultaneously for good effect. During the process, keep stirring the material and remain a state of vacuum and constant temperature (acceptable temperature of the material) until the humidity of the material reaches the requirement.

 

Cool

After dried, the material needs to be cooled before discharge.

 

Discharge

The dried and cooled material is delivered to the discharge valve by the stirring arm and discharged through the valves on the side.

 

Clean

The cleaning liquid is sprayed onto the contact surface of the product by balls, and it is also used to clean the inside of the equipment between each individual production batch or when the product is changed, which is comprehensive and effective.

 

Technical Parameters

 Features

  • Additional sensors and control systems to check when the sterilization process is over.

  • Verifiable sterilization performance

  • Flanges, seals and valves of all elements are in sterile class

  • Calculation, designand manufacture complies with Pressure Vessel Directive 97/23/EG, Section VIII of ASME Pressure Vessel Code, cGMP and FDA.

  • EG Type Examination Certificate 03ATEX0246X, UL verifiedElectronic Components

  • Double-layer mechanical seal and bellows, double-acting mechanical seal, contact or non-contact gas seal and liquid sealduring no-load operation

  • Sampling valve

  • Stainless steel hydraulic pre-wiring pipe, stainless steel pre-wiring on the junction box

  • Complete automatic online cleaning system (on-line cleaning and sterilization)

 Options

  • Microwave heating function to shorten the drying process

  • Sterile version, residualremoval layer, isolator (glove box), DQ, IQ, OQ validation.

  • Fully automatic PLC control, connected to PMSX, strong current box.

 Technical Parameters

Dryer

 

Internal Area
(Ømm)

Filtering Area
(m²)

Nominal Volume
(l)

Volume of Filter Cake
(l)

Speed
(1/min)

 

Drive
(kw)

PF 50

 

0.10

50

18

55

2.2

PF 100

500

0.20

100

32

50

4.0

PF 200

640

0.32

230

80

74

4.0

PF 250

700

0.38

280

115

70

5.5

PF 350

800

0.50

400

150

60

5.5

PF 500 S

875

0.60

500

180

52

7.5

PF 500

955

0.70

640

210

46

7.5

PF 750

1050

0.85

770

340

40

7.5

PF 1000 S

1150

1.00

930

415

40

11.0

PF 1000

1270

1.26

1140

505

37

11.0

PF 1500

1380

1.50

1500

750

30

15.0

PF 2000

1600

2.00

2000

1000

30

18.5

PF 2500

1800

2.50

2500

1250

25

18.5

PF 3000

1960

3.00

3000

1500

25

22

PF 4000

2260

4.00

4000

2000

21

22

PF 5000

2535

5.00

5000

2500

18

30

PF 6000

2765

6.00

6000

3000

17

30

 

Basic Information
  • Year Established
    --
  • Business Type
    --
  • Country / Region
    --
  • Main Industry
    --
  • Main Products
    --
  • Enterprise Legal Person
    --
  • Total Employees
    --
  • Annual Output Value
    --
  • Export Market
    --
  • Cooperated Customers
    --

Send your inquiry

Choose a different language
English
Deutsch
Español
français
italiano
日本語
Português
русский
Current language:English